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Dosing and Administration

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Only Slenyto® offers an easy to swallow minitablets that are designed specifically to address the main concern of children with ASD and insomnia and enable adjustable dosing to ensure high efficacy and safety.

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Making the Most of Slenyto®:

Right dose, 30-60 minutes before bed, every night

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Slenyto® is available in two dosage forms:

 

1 mg prolonged-release melatonin 3mm pink minitablets 

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5 mg prolonged-release melatonin 3mm yellow minitablets

  • Slenyto® treatment should be evaluated and dose can be escalated every 2-3 weeks based on treatment goals:
    - Sleep onset latency < 30 minutes.
    - Longest (uninterrupted) sleep episode > 6 hours.
    - Total sleep time - according to sleep recommendations by age.

  • Recommended starting dose of Slenyto® is 2mg (2X1mg).

  • Dose should be increased to 5mg (1X5mg) or 10mg (2X5mg) according to individual response.

  • A personalized titration to optimal dose is needed.

  • Use the following treatment algorithm to optimize Slenyto® dosing for your patient.

  • Slenyto® dose is not age/weight dependent.

For more information on how to manage Slenyto treatment click below:

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Download Treatment Algorithm >

 

  • After at least 6 months of treatment, the physician should evaluate Slenyto® treatment effect.

  • Doctor may consider stopping if no clinically relevant treatment effect is observed.

  • If a lower treatment effect is observed after titration to a higher dose, the prescriber should first consider a down-titration to a lower dose before deciding on a complete discontinuation of treatment.

Slenyto designed with children in mind

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1 mg

5 mg

Slenyto 1 mg minitablet
Slenyto 5mg mintablet

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1 cm
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Taking Slenyto is Easy

Slenyto is easy to swallow mintablet
Slenyto is easy to swallow mintablet

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Easy to swallow minitablet

Slenyto should be taken daily, at night.

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Should be taken daily, at night, 30-60 minutes before bedtime

Slenyto may be taken with a glass of water, yogurt, orange juice or ice-cream.

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May be taken with a glass of water. Alternatively it may be put into food such as yogurt, orange juice or ice-cream to help with swallowing

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  • Slenyto® should be taken as soon as the tablet is out of  the blister pack 

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  • It should not be crushed or chewed

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  • If the child misses a dose of Slenyto®, it could be taken before they go to sleep that night.

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The full list of excipients is available in the Summary of Product Characteristics (SPC).


* Minitablets shown are not in actual size.

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